TARGETED INDUSTRIES
An ever-growing and in-demand workforce, stellar infrastructure across the region, and a business-friendly tax environment are just a few reasons why many companies launch or expand their businesses in the Sioux Metro. We invite you to join our diversified economy alongside numerous regionally known and nationally renowned businesses that continue to establish our unrivaled corporate community.
MAKE MOVES IN THE SIOUX METRO
Whether you conduct business by rail, air, or road, the greater Sioux Falls region is equipped to support your growth. With access to two major interstates, a regional airport with daily national connections, and a strong freight rail network, the Sioux Metro serves as a vital transportation launchpad. Our central location, cost-effective infrastructure, and reliable distribution systems make the region a top choice for logistics, warehousing, and supply chain operations across the Midwest.
ADVANCE YOUR WORLD IN THE SIOUX METRO
The greater Sioux Falls region is home to a wide range of advanced manufacturers who excel in producing quality goods. With unmatched access to reliable infrastructure, utilities, and telecommunication networks, the Sioux Metro offers everything your business needs to thrive. Our commitment to innovation and efficiency, combined with a centralized location and a skilled workforce, makes the region an ideal place to build and grow your manufacturing operations.
CARE FOR THE CHANGING WORLD IN SIOUX METRO
With two top-ranked hospital systems, Avera Health and Sanford Health, based in Sioux Falls, the Sioux Metro is a regional hub for healthcare. A skilled and educated workforce supports growing biotech and pharmaceutical companies such as SAB Biotherapeutics. Strong retention of graduates from USD’s Sanford School of Medicine and SDSU’s College of Pharmacy, along with access to research funding and a tax-friendly climate, makes the region ideal for advancing healthcare innovation and delivery.
PROTECT WHAT MATTERS IN THE SIOUX METRO
From centrally located, publicly available data centers to Dakota State University’s trusted cybersecurity programs in Madison, the Sioux Metro is ideal for cybersecurity and IT businesses. DSU’s partnerships with the NSA, DHS, and National Science Foundation, along with its groundbreaking Madison Cyber Labs (MadLabs), have positioned the region as one of the nation’s fastest growing cybersecurity centers. Discover how innovation and infrastructure meet in the Sioux Metro.
REALIZE A RETURN ON INVESTMENT IN SIOUX METRO
Financial services are among South Dakota’s most established industries, thanks in large part to the state’s pro-business regulatory climate. With a long history of business-friendly rules, the Sioux Metro is a prime location for banking, insurance, and financial technology firms. That’s why regional and national institutions such as Citi, Sammons Financial, and First PREMIER Bank/PREMIER Bankcard have made Sioux Falls home and continue to invest in the region’s economic future.
GROW YOUR FUTURE IN THE SIOUX METRO
Agriculture is at the root of South Dakota’s economy, both historically and today. From value-added agriculture and food processing to livestock development, the state’s agricultural legacy runs deep. Add in vast, fertile land, advanced precision agriculture technologies, and a hardworking Midwestern labor force, and it is easy to see why ag-based companies continue to plant roots in the Sioux Metro. Our region is built to support sustainable and innovative agricultural growth.


